Program Announcement for the Armed Forces Institute of Regenerative Medicine (AFIRM)
Fiscal Year 2025 (FY25)
Advancing Therapeutic Reprogramming for Military Regenerative Medicine
Announcement Type: Initial
Funding Opportunity Number: AFIRM 002
Solicitation release by the Wake Forest Institute for Regenerative Medicine
The AFIRM Coordinating Center
URGENT NOTICE: The White Paper due date for the AFIRM 002 funding opportunity, Advancing Therapeutic Reprogramming for Military Regenerative Medicine, has been changed. The new due date will be 14 calendar days after the Federal Government resumes normal operations, that is, a budget agreement has been reached, and Federal Workers have returned to their positions (no longer furloughed). The submission time will remain Noon, US Eastern time zone. An exact date will be posted on this website after the Federal Government resumes normal operations.
The FY25 AFIRM Focus Areas are listed in below:
- Focus Area #1: Craniomaxillofacial Regeneration
- Focus Area #2: Extremity Regeneration
- Focus Area #3: Genitourinary/lower abdomen Reconstruction
- Focus Area #4: Skin Regeneration
- Focus Area #5: Ex-vivo/on demand Blood
- Focus Area #6: Cellular therapies for Trauma and Critical Care
NOTE: If you are including a clinical trial in your proposal, you must upload the Clinical Trial Study/Timeline Schedule in Attachment 2. If you are not including a clinical trial, upload a document stating that the study timeline is not applicable. A document must be uploaded in Attachment 2 for your proposal submission to be complete.
Submission and Review Dates
Request Issue Date: August 18, 2025
URGENT NOTICE: The White Paper due date for the AFIRM 002 funding opportunity, Advancing Therapeutic Reprogramming for Military Regenerative Medicine, has been changed. The new due date will be 14 calendar days after the Federal Government resumes normal operations, that is, a budget agreement has been reached, and Federal Workers have returned to their positions (no longer furloughed). The submission time will remain Noon, US Eastern time zone. An exact date will be posted on this website after the Federal Government resumes normal operations.
Peer Review: November 2025
Programmatic Review: December 2025
Award Negotiations Begin: February 2026